ABSTRACT
Correlation between various epidemiological factors and carcinoma cervix patients in North Bengal zone has been studied for the first time. Significant correlation between elderly women (41-50 years age group), low socio-economic status (SES), first coitus before 17 years of age, low literacy rate and this illness has been established. Suggestion has been made for improvement of the picture. Oncology and radiotherapy department of North Bengal Medical College and Hospital should be utilised as the centre for National Cancer Registration Project in North Bengal zone.
Subject(s)
Adolescent , Adult , Aged , Cross-Sectional Studies , Developing Countries , Female , Humans , Incidence , India/epidemiology , Middle Aged , Population Surveillance , Risk Factors , Uterine Cervical Neoplasms/epidemiologyABSTRACT
Clinicopathological features of 26 cases of bronchogenic carcinoma in patients below the age of 40 years have been studied and compared with 271 cases of bronchogenic carcinoma occurring in elderly patients. There was female preponderance (19.23%) in the younger study group compared to the elderly group (6.6%) and increased incidence of smokers in the younger group (57.6% versus 79.3%) and had achieved statistical significance (p < 0.001). Majority (20 out of 26) had a rural background. All the patients were symptomatic at the time of diagnosis and all the 26 cases except one belonged to advanced stage. The incidence of squamous cell carcinoma was almost same for both the age groups. Eighteen of the 26 cases had received antituberculosis chemotherapy by general practitioners before referral to the specialists. Twenty patients were treated initially by palliative radiotherapy and then by chemotherapy.
Subject(s)
Adult , Age Factors , Carcinoma, Bronchogenic/diagnosis , Female , Humans , Lung Neoplasms/diagnosis , Male , SmokingSubject(s)
Animals , Brain/metabolism , Hyperthyroidism/metabolism , Hypothyroidism/metabolism , Male , Rats , Tretinoin/metabolismABSTRACT
The prednisolone has got a devastating effect on the creatine content of muscle when it is tenotomised. In non-tenotomised muscle, prednisolone reduces the creatine content. The reduction of creatine content in prednisolone treated muscle which are tenotomised is due to perhaps the catabolic effect of glucocorticoid analogue on muscle protein together with inactivity of the muscle.